Title
Improved Generation Of Probabilistic Atlases For The Expectation Maximization Classification
Abstract
Probabilistic atlases present prior knowledge about the spatial distribution of various structures or tissues in a population, used commonly in segmentation. We propose three methods for generating probabilistic atlases: 1) the atlases are constructed in a template space using dense non-rigid transformations and transformed to the space of unseen data, 2) as the method 1 but atlas selection is performed in addition, and 3) the atlases are constructed directly in the space of the unseen data. The methods were evaluated in the segmentation of the hippocampus in 340 images from the Alzheimer's Disease Neuroimaging Initiaitve (ADNI). Dice overlaps (similarity index, SI) were 0.84, 0.85 and 0.87 with reference segmentations and the correlation coefficients for the volumes were 0.84, 0.92 and 0.96 for the three methods tested. Our results show clearly the importance of probabilistic atlases in segmentation.
Year
DOI
Venue
2011
10.1109/ISBI.2011.5872765
2011 8TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO
Keywords
Field
DocType
probabilistic atlases, segmentation, structural MRI images, Alzheimer's disease
Computer vision,Population,Probabilistic atlas,Pattern recognition,Computer science,Expectation–maximization algorithm,Segmentation,Image segmentation,Correlation,Artificial intelligence,Probabilistic logic,Contextual image classification
Conference
ISSN
Citations 
PageRank 
1945-7928
3
0.42
References 
Authors
9
8
Name
Order
Citations
PageRank
Jyrki Lötjönen138833.95
Robin Wolz266134.42
Juha Koikkalainen3558.46
Lennart Thurfjell414010.50
Roger Lundqvist5261.76
Gunhild Waldemar61095.72
Hilkka Soininen71498.31
Daniel Rueckert89338637.58