Title
Prefrontal Cortex Modulation during Anticipation of Working Memory Demands as Revealed by Magnetoencephalography.
Abstract
During the anticipation of task demands frontal control is involved in the assembly of stimulus-response mappings based on current goals. It is not clear whether prefrontal modulations occur in higher-order cortical regions, likely reflecting cognitive anticipation processes. The goal of this paper was to investigate prefrontal modulation during anticipation of upcoming working memory demands as revealed by magnetoencephalography (MEG). Twenty healthy volunteers underwent MEG while they performed a variation of the Sternberg Working Memory (WM) task. Beta band (14-30 Hz) SAM (Synthetic Aperture Magnetometry) analysis was performed. During the preparatory periods there was an increase in beta power (event-related synchronization) in dorsolateral prefrontal cortex (DLPFC) bilaterally, left inferior prefrontal gyrus, left parietal, and temporal areas. Our results provide support for the hypothesis that, during preparatory states, the prefrontal cortex is important for biasing higher order brain regions that are going to be engaged in the upcoming task.
Year
DOI
Venue
2010
10.1155/2010/840416
Int. J. Biomedical Imaging
Keywords
Field
DocType
task demands frontal control,prefrontal cortex,preparatory period,prefrontal cortex modulation,memory demand,preparatory state,upcoming task,left parietal,prefrontal modulation,dorsolateral prefrontal cortex,inferior prefrontal gyrus,cognitive anticipation process,magnetoencephalography,bioinformatics,biomedical research,text mining,working memory
Synthetic-aperture magnetometry,Consumer neuroscience,Computer vision,Neuroscience,Anticipation,Computer science,Dorsolateral prefrontal cortex,Prefrontal cortex,Working memory,Interference theory,Artificial intelligence,Magnetoencephalography
Journal
Volume
ISSN
Citations 
2010
1687-4196
1
PageRank 
References 
Authors
0.37
4
7