Title
Apparent intravoxel fibre population dispersion (FPD) using spherical harmonics.
Abstract
The vast majority of High Angular Resolution Diffusion Imaging (HARDI) modeling methods recover networks of neuronal fibres, using a heuristic extraction of their local orientation. In this paper, we present a method for computing the apparent intravoxel Fibre Population Dispersion (FPD), which conveys the manner in which distinct fibre populations are partitioned within the same voxel. We provide a statistical analysis, without any prior assumptions on the number or size of these fibre populations, using an analytical formulation of the diffusion signal autocorrelation function in the spherical harmonics basis. We also propose to extract features of the FPD obtained in the group of rotations, using several metrics based on unit quaternions. We show results on simulated data and on physical phantoms, that demonstrate the effectiveness of the FPD to reveal regions with crossing tracts, in contrast to the standard anisotropy measures.
Year
DOI
Venue
2011
10.1007/978-3-642-23629-7_20
MICCAI (2)
Keywords
Field
DocType
high angular resolution diffusion,spherical harmonic,apparent intravoxel fibre population,local orientation,analytical formulation,fibre population dispersion,heuristic extraction,distinct fibre population,apparent intravoxel,diffusion signal autocorrelation function,fibre population,neuronal fibre
Voxel,Population,Dispersion (optics),Anisotropy,Fourier analysis,Biological system,Pattern recognition,Computer science,Spherical harmonics,Euler angles,Artificial intelligence,Autocorrelation
Conference
Volume
Issue
ISSN
14
Pt 2
0302-9743
Citations 
PageRank 
References 
5
0.56
7
Authors
4
Name
Order
Citations
PageRank
Haz-Edine Assemlal1925.59
Jennifer S W Campbell225518.91
Bruce Pike381.01
Kaleem Siddiqi43259242.07