Title
Stochastic Modelling of the Kai-based Circadian Clock
Abstract
We present two process algebra models of a Kai-protein based circadian clock. Our models are represented in the Bio-PEPA and the continuous pi-calculus process algebras. The circadian clock is not based on transcription and has been shown to persist with a rhythmic signal when removed from a living cell. Our models allow us to speculate as to the mechanisms which allow for the rhythmic signals. We reproduce previous results based on ODE models and then use our models as the basis for stochastic simulation.
Year
DOI
Venue
2013
10.1016/j.entcs.2013.07.004
Electronic Notes in Theoretical Computer Science
Keywords
DocType
Volume
ode model,living cell,stochastic modelling,kai-based circadian clock,continuous pi-calculus process algebra,process algebra model,rhythmic signal,stochastic simulation,previous result,circadian clock
Journal
296,
ISSN
Citations 
PageRank 
1571-0661
1
0.36
References 
Authors
4
7
Name
Order
Citations
PageRank
Chris Banks110.70
Allan Clark225913.74
Anastasis Georgoulas3183.42
Stephen Gilmore410.36
Jane Hillston51657125.09
Dimitrios Milios6595.84
Ian Stark728018.14