Title
Design of a brain tissue scanner
Abstract
A brain tissue scanner for massively parallel tracing of neurons and mapping of their mutual connections is described. The tissue scanner (currently in design) works as follows: From an opaque tissue block, consecutive 1 mu m sections of tissue are milled off. Each newly exposed surface is scanned at the limit of optical resolution to generate a volumetric data set of the brain tissue. All brain tissue is destroyed by the sectioning. Starting with volumetric data sets generated by the tissue scanner, virtual microscopy software (Burton, McCormick Neurocomputing, 1999, in press) reconstructs the stained neurons and fibers of the tissue and recreates the virtual environment at the cellular and tissue level. (C) 1999 Published by Elsevier Science B.V. All rights reserved.
Year
DOI
Venue
1999
10.1016/S0925-2312(99)00100-9
NEUROCOMPUTING
Keywords
Field
DocType
brain tissue scanning,physical sectioning,surface scanning,virtual microscopy
Computer vision,Virtual machine,Pattern recognition,Virtual microscopy,Massively parallel,Software,Scanner,Artificial intelligence,Volumetric data,Mathematics,Tracing,Brain tissue
Journal
Volume
ISSN
Citations 
26-7
0925-2312
5
PageRank 
References 
Authors
5.07
2
1
Name
Order
Citations
PageRank
Bruce H. McCormick1134184.45