Title
Minimal realization of the dynamical structure function and its application to network reconstruction
Abstract
Network reconstruction, i.e., obtaining network structure from data, is a central theme in systems biology, economics and engineering. In some previous work, we introduced dynamical structure functions as a tool for posing and solving the problem of network reconstruction between measured states. While recovering the network structure between hidden states is not possible since they are not measured, in many situations it is important to estimate the minimal number of hidden states in order to understand the complexity of the network under investigation and help identify potential targets for measurements. Estimating the minimal number of hidden states is also crucial to obtain the simplest state-space model that captures the network structure and is coherent with the measured data. This paper characterizes minimal order state-space realizations that are consistent with a given dynamical structure function by exploring properties of dynamical structure functions and developing an algorithm to explicitly obtain such a minimal realization.
Year
Venue
Field
2012
CoRR
Mathematical optimization,Systems biology,Structure function,Minimal realization,Mathematics,Network structure
DocType
Volume
Citations 
Journal
abs/1209.3808
0
PageRank 
References 
Authors
0.34
3
4
Name
Order
Citations
PageRank
Ye Yuan143861.04
Guy-bart Stan228126.54
Sean Warnick319825.76
Jorge M. Goncalves4324.61