Name
Abstract | ||
|---|---|---|
The paper describes a new approach to the prediction of probable biological units from protein structures obtained by means of protein crystallography. The method first employs graph-theoretical technique in order to find all possible assemblies in crystal. In second step, found assemblies are analysed for chemical stability and only stable oligomers are left as a potential solution. We also discuss theoretical models for the assessment of protein affinity and entropy loss on complex formation, used in stability analysis. |
Year | DOI | Venue |
|---|---|---|
2005 | 10.1007/11560500_15 | CompLife |
Keywords | Field | DocType |
protein crystallography,stability analysis,protein structure | Graph theory,Chemical physics,Discrete mathematics,X-ray crystallography,Chemical stability,Computer science,Crystal,Theoretical models,Bioinformatics,Salt bridge,Protein structure | Conference |
Volume | ISSN | ISBN |
3695 | 0302-9743 | 3-540-29104-0 |
Citations | PageRank | References |
2 | 0.46 | 4 |
Authors | ||
2 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Evgeny B. Krissinel | 1 | 153 | 37.51 |
| Kim Henrick | 2 | 553 | 79.58 |