Title
An Algorithm For Recomputing Concepts In Microarray Data Analysis By Biological Lattice
Abstract
A data-analytic system is proposed for microarray gene expression data based on Formal Concept Analysis (FCA). The purpose of the system is to systematically organize data and to build a complete lattice that analyzes complex relations among genes and give biological interpretation of microarray data. In the system, formal concept analysis handles complex relations, so the microarray data is binarized by setting up a threshold. When change occurs in a conventional algorithm, formal concepts that are nodes of the lattice were calculated from the beginning, but the calculation is inefficient. This paper proposes a new algorithm that has two phase of matrix detection and updating concepts to efficiently update only altered concepts from previously generated concepts. Experiments on run time show that the algorithm takes an average of 0.94 seconds to process real microarray data containing of 43,734 genes and 6 gene expression values.
Year
DOI
Venue
2013
10.20965/jaciii.2013.p0761
JOURNAL OF ADVANCED COMPUTATIONAL INTELLIGENCE AND INTELLIGENT INFORMATICS
Keywords
Field
DocType
microarray, formal concept analysis, lattice theory, bioinformatics
Data mining,Lattice (order),Computer science,Microarray analysis techniques,Artificial intelligence,Formal concept analysis,Machine learning
Journal
Volume
Issue
ISSN
17
5
1343-0130
Citations 
PageRank 
References 
0
0.34
7
Authors
6
Name
Order
Citations
PageRank
Hidenobu Hashikami120.73
Takanari Tanabata261.97
Fumiaki Hirose361.50
Nur Hasanah420.72
Kazuhito Sawase552.87
Hajime Nobuhara619234.02