Title
Deciphering the Genetic Blueprint of Cerebellar Development by the Gene Expression Profiling Informatics
Abstract
The brain is the ultimate genetic system to which a large number of genes are devoted. To extract and visualize biological information from such large data sets accumulated in the post-sequencing era, the use of bioinformatics would be a very powerful means. To understand the genetic basis of mouse cerebellar postnatal development, we have analyzed the whole transcription or gene expression (transcriptome) during the developmental stages on a genome-wide basis, and have systematized the spatio-temporal gene expression profile information in a comprehensive database (Cerebellar Development Transcriptome [CDT] database) from a bioinformatics point of view. This CDT database would open up a new field for deciphering the genetic blueprint for cerebellar development.
Year
DOI
Venue
2004
10.1007/978-3-540-30499-9_135
Lecture Notes in Computer Science
Keywords
Field
DocType
genetics,gene expression
Gene,Computer science,Gene mapping,Transcriptome,Artificial intelligence,Computational biology,Informatics,Transcription (biology),Gene expression,Blueprint,Bioinformatics,Machine learning,Gene expression profiling
Conference
Volume
ISSN
Citations 
3316
0302-9743
2
PageRank 
References 
Authors
0.59
1
14