Paper Info
Title
User-friendly software for the analysis of brain lesions (ABLe).
Abstract
We previously developed a software package called ABLe (analysis of brain lesions) which characterizes brain lesions in terms of lesion volume and intersection with cytoarchitecture (e.g. Brodmann areas). Since our previous publication, there have been significant improvements to this software package which utilize methods standard to the neuroimaging community. These features include spatial normalization to the MNI template brain (standard of the international consortium for brain mapping), and use of the volume occupancy Talairach labels (VOTL) and automated anatomical labeling (AAL) atlases for full brain quantification of structures impacted by the lesion. Methods for multi-subject studies including lesion-symptom mapping proposed by Bates et al. have been extended in ABLe to produce an exploratory analysis summarizing correlations between subjects with overlapping lesions and behavioral deficit. A subset of data from an ongoing traumatic head injury study correlating deficit with brain anatomy is used to demonstrate the power of this software package.
Year
DOI
Venue
2007
10.1016/j.cmpb.2007.02.006
Computer Methods and Programs in Biomedicine
Keywords
Field
DocType
software package,brain anatomy,brain lesion,brain mapping,exploratory analysis,lesion volume,mni template brain,lesion-symptom mapping,full brain quantification,behavioral deficit,user-friendly software,diagnostic imaging,cytoarchitecture
Brain mapping,Lesion,Computer science,Medical imaging,Software,Cytoarchitecture,Artificial intelligence,Neuroimaging,Pathology,Computer vision,Pattern recognition,Prefrontal cortex,Spatial normalization
Journal
Volume
Issue
ISSN
86
3
0169-2607
Citations 
PageRank 
References 
8
0.78
3
Authors
5
Name
Order
Citations
PageRank
Jeffrey Solomon1234.37
Vanessa Raymont2133.22
Allen Braun3121.58
John A. Butman45211.18
Jordan Grafman57313.61