Name
Title | ||
|---|---|---|
A comparison of the cingulum tract in ALS-B patients and controls using kernel matching |
Abstract | ||
|---|---|---|
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease with poor prognosis. Previous DW-MRI based studies in ALS on WM tracts showed a decrease of FA in tracts related to the motor system. Recent evidence suggests that extra-motor tracts are also affected by ALS. This paper aims to analyse the cingulum tracts of ALS patients and controls. To do so, we introduce kernel matching, a novel method to obtain optimal correspondence between the white matter tracts. The orientation of tract tensors in atlas space as well as the global tract shape are employed as prior information. The method proved successful to reduce the large variance of tensor shape features along the cinguli emanating from registration errors. Only after applying the proposed kernel matching method we found a significant increase in the tensor norm of both cinguli. We hypothesize that the degeneration of fibers increases tensor norm. |
Year | DOI | Venue |
|---|---|---|
2010 | 10.1007/978-3-642-15745-5_31 | Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention |
Keywords | Field | DocType |
novel method,tensor shape feature,extra-motor tract,tensor norm,wm tract,als patient,cinguli emanating,als-b patient,kernel matching,cingulum tract,global tract shape,motor system | Diffusion MRI,Anatomy,Tensor,White matter,Computer science,Artificial intelligence,Motor system,Progressive motor neuron disease,Pathology,Kernel (linear algebra),Pattern recognition,Fractional anisotropy,Amyotrophic lateral sclerosis | Conference |
Volume | Issue | ISSN |
13 | Pt 2 | 0302-9743 |
ISBN | Citations | PageRank |
3-642-15744-0 | 4 | 0.54 |
References | Authors | |
13 | 5 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Sander van Noorden | 1 | 4 | 0.54 |
| Matthan Caan | 2 | 20 | 2.77 |
| Maaike van der Graaff | 3 | 4 | 0.54 |
| Lucas van Vliet | 4 | 4 | 0.54 |
| Frans Vos | 5 | 106 | 11.97 |