Abstract | ||
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In patients with Parkinson’s disease, deep brain stimulation of the subthalamic nucleus is known to impair their ability to correctly identify facial expressions of negative emotions. This difficulty exists only when the stimulator is active. The reason for the impairment is unknown. To test the hypothesis that the stimulation itself is responsible, we used positron emission tomography to compare functional activations of brain regions in nine patients with Parkinson’s disease treated with surgically implanted electrodes into both subthalamic nuclei, and 22 healthy volunteers. Both groups viewed images with neutral or emotional content from Aarhus University’s standard Empathy Picture System (www.geday.net/eps) with 360 images of people in pleasant, unpleasant or neutral real-life situations, presenting either the situations or close-ups of the facial expressions of the people involved. |
Year | DOI | Venue |
---|---|---|
2006 | 10.1016/j.neuroimage.2006.06.056 | NeuroImage |
Keywords | Field | DocType |
Parkinson,Subthalamic nucleus (STN),Emotion,Facial expression,Fusiform gyrus | Empathy,Developmental psychology,Deep brain stimulation,Putamen,Neuroscience,Cognitive psychology,Psychology,Facial expression,Fusiform gyrus,Stimulus (physiology),Subthalamic nucleus,Stimulation | Journal |
Volume | Issue | ISSN |
33 | 2 | 1053-8119 |
Citations | PageRank | References |
0 | 0.34 | 2 |
Authors | ||
3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Jacob Geday | 1 | 0 | 0.34 |
Karen Ostergaard | 2 | 0 | 0.34 |
A GJEDDE | 3 | 40 | 9.87 |