Title
T1dbase: Integration And Presentation Of Complex Data For Type 1 Diabetes Research
Abstract
T1DBase (http://T1DBase.org) [Smink et al. (2005) Nucleic Acids Res., 33, D544-D549; Burren et al. (2004) Hum. Genomics, 1, 98-109] is a public website and database that supports the type 1 diabetes (T1D) research community. T1DBase provides a consolidated T1D-oriented view of the complex data world that now confronts medical researchers and enables scientists to navigate from information they know to information that is new to them. Overview pages for genes and markers summarize information for these elements. The Gene Dossier summarizes information for a list of genes. GBrowse [Stein et al. (2002) Genome Res., 10, 1599-1610] displays genes and other features in their genomic context, and Cytoscape [Shannon et al. (2003) Genome Res., 13, 2498-2504] shows genes in the context of interacting proteins and genes. The Beta Cell Gene Atlas shows gene expression in beta cells, islets, and related cell types and lines, and the Tissue Expression Viewer shows expression across other tissues. The Microarray Viewer shows expression from more than 20 array experiments. The Beta Cell Gene Expression Bank contains manually curated gene and pathway annotations for genes expressed in b cells. T1DMart is a query tool for markers and genotypes. PosterPages are 'home pages' about specific topics or datasets. The key challenge, now and in the future, is to provide powerful informatics capabilities to T1D scientists in a form they can use to enhance their research.
Year
DOI
Venue
2007
10.1093/nar/gkl933
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
systems integration,internet,nucleic acid,gene expression profiling,complex data,gene expression
Genome,Informatics,Gene,Biology,Complex data type,Gene expression,Cell type,Genomics,Genetics,Gene expression profiling
Journal
Volume
Issue
ISSN
35
Database-Issue
0305-1048
Citations 
PageRank 
References 
10
2.69
12
Authors
20