Name
Abstract | ||
|---|---|---|
In recent developments in chemistry and genetic engineering, the humble researcher dealing with the origin of life finds her(him)self in a grey area of tackling something that even does not yet have a clear definition agreed upon. A series of chemical steps is described to be considered as the life–nonlife transition, if one adheres to the minimalistic definition: life is self-reproduction with variations. The fully artificial RNA system chosen for the exploration corresponds sequence-wise to the reconstructed initial triplet repeats, presumably corresponding to the earliest protein-coding molecules. The demonstrated occurrence of the mismatches (variations) in otherwise complementary syntheses (“self-reproduction”), in this RNA system, opens an experimental and conceptual perspective to explore the origin of life (and its definition), on the apparent edge of the origin. |
Year | DOI | Venue |
|---|---|---|
2011 | 10.1016/S1672-0229(11)60002-8 | Genomics, Proteomics & Bioinformatics |
Keywords | Field | DocType |
triplet code,origin of life,definition of life,life–nonlife transition | Abiogenesis,Observable,Biology,Genetics,Evolutionary biology | Journal |
Volume | Issue | ISSN |
9 | 1 | 1672-0229 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
3 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Samanta Pino | 1 | 0 | 0.68 |
| Edward N Trifonov | 2 | 75 | 20.54 |
| E Di Mauro | 3 | 0 | 1.01 |