Title
A Framework for Three-Dimensional Simulation of Morphogenesis
Abstract
We present CompuCell3D, a software framework for three-dimensional simulation of morphogenesis in different organisms. CompuCell3D employs biologically relevant models for cell clustering, growth, and interaction with chemical fields. CompuCell3D uses design patterns for speed, efficient memory management, extensibility, and flexibility to allow an almost unlimited variety of simulations. We have verified CompuCell3D by building a model of growth and skeletal pattern formation in the avian (chicken) limb bud. Binaries and source code are available, along with documentation and input files for sample simulations, at http://compucell.sourceforge.net.
Year
DOI
Venue
2005
10.1109/TCBB.2005.46
IEEE/ACM Trans. Comput. Biology Bioinform.
Keywords
Field
DocType
extensible markup language,cellular automata,design pattern,morphogenesis,reaction diffusion,source code,memory management,three dimensional,software framework,source coding,pattern formation
Cellular automaton,Source code,Computer science,Software design pattern,Pattern formation,Memory management,Bioinformatics,Cluster analysis,Extensibility,Software framework
Journal
Volume
Issue
ISSN
2
4
1545-5963
Citations 
PageRank 
References 
25
2.49
8
Authors
9