Name
Abstract | ||
|---|---|---|
Electrochemical behaviors of DNA (Deoxyribonucleic acid) are studied for exploring label free PCR (Polymerase Chain Reaction) detection used in miniaturized PCR system. PCR chips with three electrodes are fabricated with CMOS (Complementary Metal Oxide Semiconductor) compatible process. Micro electrodes with different metals successfully are obtained inside the micro PCR reaction cell for optimizing the electrochemical process. Both purified DNA solution diluted in PBS buffer and amplified DsRed DNA solution of n (n=0,4,8,12,20) cycles are used as the solution system. The experiment revealed that the redox peaks current difference between DsRed DNA solution of 4 cycles and 12 cycles is 50 nA. |
Year | DOI | Venue |
|---|---|---|
2011 | 10.1109/NEMS.2011.6017512 | NEMS |
Keywords | Field | DocType |
dsred dna,pcr product,cmos compatible process,purified dna solution,micropcr reaction cell,polymerase chain reaction,pcr chips,pcr amplification,pbs buffer,electrochemical electrodes,enzymes,micro pcr,biological techniques,dsred dna solution,biochemistry,molecular biophysics,redox peaks,complementary metal oxide semiconductor,label-free micropcr application,lab-on-a-chip,microelectrodes,deoxyribonucleic acid,dna,dna electrochemical behavior,purification,electrochemical,chip,lab on a chip | Analytical chemistry,Polymerase chain reaction,DNA,Molecular biophysics,Lab-on-a-chip,Electrochemistry,Materials science,Electrode,Microelectrode,Redox | Conference |
Volume | Issue | ISBN |
null | null | 978-1-61284-775-7 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Rong Zhang | 1 | 0 | 0.34 |
| Jian Qin | 2 | 0 | 0.34 |
| Hao Tian | 3 | 5 | 3.78 |
| Weihua Si | 4 | 0 | 0.34 |
| Taihong Wang | 5 | 0 | 0.34 |
| Zewen Liu | 6 | 2 | 5.78 |