Name
Abstract | ||
|---|---|---|
Fluorescent X-ray CT (FXCT), which has high-contrast and high-spatial resolution, is being developed for in-vivo biomedical research. Since FXCT could depict the specific heavy atomic number elements in the order of picogram, the functional imaging resembling to single photon emission CT can be obtained. We have applied this technique for in-vivo and ex-vivo biomedical imaging. FXCT system consists of a silicon (111) double crystal monochromator, an x-ray slit system, a scanning table for object positioning, fluorescent x-ray detectors, and pin-diode detectors. Using non-radioactive iodine labeled IMP, cerebral perfusion of a live mouse was clearly demonstrated at a 1 mm spatial resolution and a 0.1 mm slice thickness. In addition, the structure of extracted mouse brain fixed by formalin was depicted much clearly at 0.5 mm spatial resolution due to the availability of long data acquisition time. Thus, the success of in-vivo FXCT imaging with high resolution allows starting to new approach of bio-imaging research. |
Year | DOI | Venue |
|---|---|---|
2005 | 10.1109/ICIP.2005.1530461 | ICIP (3) |
Keywords | Field | DocType |
x-ray slit system,nonradioactive iodine labeled imp,cerebral blood flow,cerebral perfusion imaging,fluorescent x-ray detectors,diagnostic radiography,computerised tomography,object positioning,in-vivo imaging,fluorescent x-ray ct,pin-diode detectors,image resolution,synchrotron radiation,high-contrast,silicon double crystal monochromator,fluorescence,cerebral perfusion,biomedical imaging,high-spatial resolution,scanning table,brain,single photon emission,live mice,mouse,in-vivo biomedical research,medical image processing,in vivo imaging,high resolution,x ray detector,spatial resolution,data acquisition,functional imaging | Biomedical engineering,Computer vision,Photon emission,X-ray,Computer science,Medical imaging,Fluorescence,Artificial intelligence,Slice thickness,Crystal monochromator,Cerebral perfusion pressure,Image resolution | Conference |
Volume | ISSN | ISBN |
3 | 1522-4880 | 0-7803-9134-9 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
9 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Tohoru Takeda | 1 | 5 | 1.16 |
| Jin Wu | 2 | 0 | 0.34 |
| Thet-thet-lwin | 3 | 0 | 0.34 |
| Naoki Sunaguchi | 4 | 0 | 3.04 |
| Tetsuya Yuasa | 5 | 5 | 3.87 |
| Kazuyuki Hyodo | 6 | 5 | 4.21 |
| F. Avraham Dilmanian | 7 | 3 | 0.81 |
| M. Minami | 8 | 0 | 0.68 |
| Takao Akatsuka | 9 | 6 | 1.52 |