Paper Info
Title
A Constrained Non-rigid Registration Algorithm for Use in Prostate Image-Guided Radiotherapy
Abstract
A constrained non-rigid registration (CNRR) algorithm for use in updating prostate external beam image-guided radiotherapy treatment plans is presented in this paper. The developed algorithm is based on a multi-resolution cubic B-spline FFD transformation and has been tested and verified using 3D CT images from 10 sets of real patient data acquired from 4 different patients on different treatment days. The registration can be constrained to any combination of the prostate, rectum, bladder, pelvis, left femur, and right femur. The CNRR was tested with 5 different combinations of constraints and each test significantly outperformed both rigid and non-rigid registration at aligning constrained bones and critical organs. The CNRR was then used to update the treatment plans to account for articulated, rigid bone motion and non-rigid organ deformation. Each updated treatment plan outperformed the original treatment plan by increasing radiation dosage to the prostate and lowering radiation dosage to the rectum and bladder.
Year
DOI
Venue
2008
10.1007/978-3-540-85988-8_93
MICCAI
Keywords
Field
DocType
treatment planning
Computer vision,Computer science,Algorithm,Free-form deformation,Radiation therapy,Prostate,Artificial intelligence,Left femur,Right femur,Radiology,Pelvis,Dose-volume histogram
Conference
Volume
Issue
ISSN
11
Pt 1
0302-9743
Citations 
PageRank 
References 
5
0.68
6
Authors
8
Name
Order
Citations
PageRank
William Harvey Greene150.68
Sudhakar Chelikani2605.20
Kailas Purushothaman350.68
Zhe Chen4718.05
Jonathan Knisely5271.66
Lawrence H. Staib652663.63
Xenophon Papademetris751648.77
James S. Duncan82973466.48