Title
Dissociable neural effects of long-term stimulus-reward pairing in macaque visual cortex.
Abstract
It has been proposed that perceptual learning may occur through a reinforcement process, in which consistently pairing stimuli with reward is sufficient for learning. We tested whether stimulus–reward pairing is sufficient to increase the sensorial representation of a stimulus by recording local field potentials (LFPs) in macaque extrastriate area V4 with chronically implanted electrodes. Two oriented gratings were repeatedly presented; one was paired with a fluid reward, whereas no reward was given at any other time. During the course of conditioning the LFP increased for the rewarded compared to the unrewarded orientation. The time course of the effect of stimulus–reward pairing and its reversal differed between an early and late interval of the LFP response: a fast change in the later part of the neural response that was dissociated from a slower change in the early part of the response. The fast change of the late interval LFP suggests that this late LFP change is related to enhanced attention during the presentation of the rewarded stimulus. The slower time course of the early interval response suggests an effect of sensorial learning. Thus, simple stimulus–reward pairing is sufficient to strengthen stimulus representations in visual cortex and does this by means of two dissociable mechanisms.
Year
DOI
Venue
2010
10.1162/jocn.2009.21288
Cognitive Neuroscience, Journal of
Keywords
Field
DocType
late lfp change,dissociable neural effect,early interval response,simple stimulus-reward pairing,lfp response,neural response,slower change,stimulus-reward pairing,macaque visual cortex,long-term stimulus-reward,pairing stimulus,late interval,fast change,perceptual learning,local field potential
Neuroscience,Visual cortex,Macaque,Perceptual learning,Psychology,Cognitive psychology,Pairing,Conditioning,Local field potential,Stimulus (physiology),Reinforcement
Journal
Volume
Issue
ISSN
22
7
1530-8898
Citations 
PageRank 
References 
8
0.72
1
Authors
3
Name
Order
Citations
PageRank
Frank E. Pollick127438.14
Aaron R Seitz282.07
Rufin Vogels3477.82