Title
Entrez Neuron RDFa: a pragmatic semantic web application for data integration in neuroscience research.
Abstract
The amount of biomedical data available in Semantic Web formats has been rapidly growing in recent years. While these formats are machine-friendly, user-friendly web interfaces allowing easy querying of these data are typically lacking. We present "Entrez Neuron", a pilot neuron-centric interface that allows for keyword-based queries against a coherent repository of OWL ontologies. These ontologies describe neuronal structures, physiology, mathematical models and microscopy images. The returned query results are organized hierarchically according to brain architecture. Where possible, the application makes use of entities from the Open Biomedical Ontologies (OBO) and the 'HCLS knowledgebase' developed by the W3C Interest Group for Health Care and Life Science. It makes use of the emerging RDFa standard to embed ontology fragments and semantic annotations within its HTML-based user interface. The application and underlying ontologies demonstrate how Semantic Web technologies can be used for information integration within a curated information repository and between curated information repositories. It also demonstrates how information integration can be accomplished on the client side, through simple copying and pasting of portions of documents that contain RDFa markup.
Year
DOI
Venue
2009
10.3233/978-1-60750-044-5-317
Studies in Health Technology and Informatics
Keywords
Field
DocType
semantic web,neuroscience,OWL,web user interface,reasoning,RDFa,information integration
Ontology (information science),Data integration,Information integration,Data mining,World Wide Web,Semantic Web Stack,Information retrieval,Open Biomedical Ontologies,Computer science,Entrez,Semantic Web,Information repository
Conference
Volume
ISSN
Citations 
150
0926-9630
2
PageRank 
References 
Authors
0.42
3
10
Name
Order
Citations
PageRank
Matthias Samwald151339.34
Ernest Lim2232.49
Peter Masiar3255.21
Luis N. Marenco417233.85
Huanhuan Chen5731101.79
Thomas M Morse628637.56
Pradeep Mutalik791.59
G M Shepherd850873.75
P L Miller944593.86
Kei-hoi Cheung1066460.65