Title
Integration and visualization of host-pathogen data related to infectious diseases.
Abstract
Infectious disease research is generating an increasing amount of disparate data on pathogenic systems. There is a growing need for resources that effectively integrate, analyze, deliver and visualize these data, both to improve our understanding of infectious diseases and to facilitate the development of strategies for disease control and prevention.We have developed Disease View, an online host-pathogen resource that enables infectious disease-centric access, analysis and visualization of host-pathogen interactions. In this resource, we associate infectious diseases with corresponding pathogens, provide information on pathogens, pathogen virulence genes and the genetic and chemical evidences for the human genes that are associated with the diseases. We also deliver the relationships between pathogens, genes and diseases in an interactive graph and provide the geolocation reports of associated diseases around the globe in real time. Unlike many other resources, we have applied an iterative, user-centered design process to the entire resource development, including data acquisition, analysis and visualization.Freely available at http://www.patricbrc.org; all major web browsers supported.cmao@vbi.vt.eduSupplementary data are available at Bioinformatics online.
Year
DOI
Venue
2011
10.1093/bioinformatics/btr391
Bioinformatics
Keywords
Field
DocType
pathogen interaction,supplementary data,disparate data,entire resource development,infectious disease,pathogen resource,pathogen data,corresponding pathogen,data acquisition,infectious disease-centric access,infectious disease research,computational biology,bacteria,systems integration,virulence,computer graphics
Data mining,Graph,Disease,Computer science,Visualization,Geolocation,Disparate system,Bioinformatics,Infectious disease (medical specialty),System integration,Pathogen
Journal
Volume
Issue
ISSN
27
16
1367-4811
Citations 
PageRank 
References 
4
0.51
6
Authors
9
Name
Order
Citations
PageRank
Timothy Driscoll1452.53
Joseph L. Gabbard253050.58
chunhong mao315710.55
Oral Dalay4452.53
Maulik Shukla51107.97
Clark C. Freifeld6251.91
Anne Gatewood Hoen740.85
John S Brownstein819121.62
Bruno Sobral9736.06