Title
MGAlignIt: a web service for the alignment of mRNA/EST and genomic sequences.
Abstract
Splicing is a biological phenomenon that removes the non-coding sequence from the transcripts to produce a mature transcript suitable for translation. To study this phenomenon, information on the intron-exon arrangement of a gene is essential, usually obtained by aligning mRNA/EST sequences to their cognate genomic sequences. MGAlign is a novel, rapid, memory efficient and practical method for aligning mRNA/EST and genome sequences. We present here a freely available web service, MGAlignIt (http://origin.bic.nus.edu.sg/mgalign/mgalignit), based on MGAlign. Besides the alignment itself, this web service allows users to effectively visualize the alignment in a graphical manner and to perform limited analysis on the alignment output. The server also permits the alignment to be saved in several forms, both graphical and text, suitable for further processing and analysis by other programs.
Year
DOI
Venue
2003
10.1093/nar/gkg561
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
genome sequence,web service
Sequence alignment,Genome,Alignment-free sequence analysis,Expressed sequence tag,Biology,Genomics,RNA splicing,Multiple sequence alignment,Web service,Genetics,Molecular biology
Journal
Volume
Issue
ISSN
31
13.0
0305-1048
Citations 
PageRank 
References 
8
1.09
2
Authors
3
Name
Order
Citations
PageRank
Bernett T K Lee1424.54
Tin Wee Tan256636.14
Shoba Ranganathan368936.60