Title
Modular modeling of cellular systems with ProMoT/Diva.
Abstract
Motivation: Need for software to setup and analyze complex mathematical models for cellular systems in a modular way, that also integrates the experimental environment of the cells. Results: A computer framework is described which allows the building of modularly structured models using an abstract, modular and general modeling methodology. With this methodology, reusable modeling entities are introduced which lead to the development of a modeling library within the modeling tool ProMot. The simulation environment Diva is used for numerical analysis and parameter identification of the models. The simulation environment provides a number of tools and algorithms to simulate and analyze complex biochemical networks. The described tools are the first steps towards an integrated computer-based modeling, simulation and visualization environment.
Year
DOI
Venue
2003
10.1093/bioinformatics/btg128
BIOINFORMATICS
Keywords
Field
DocType
mathematical model,numerical analysis
Visualization,Computer science,Software,Bioinformatics,Modular design,Diva,Mathematical model
Journal
Volume
Issue
ISSN
19
9.0
1367-4803
Citations 
PageRank 
References 
25
3.91
5
Authors
5
Name
Order
Citations
PageRank
Ginkel M1968123.55
Andreas Kremling2539.60
T Nutsch3253.91
R Rehner4253.91
Ernst Dieter Gilles554455.14