Title
Learning to segment neurons with non-local quality measures.
Abstract
Segmentation schemes such as hierarchical region merging or correllation clustering rely on edge weights between adjacent (super-)voxels. The quality of these edge weights directly affects the quality of the resulting segmentations. Unstructured learning methods seek to minimize the classification error on individual edges. This ignores that a few local mistakes (tiny boundary gaps) can cause catastrophic global segmentation errors. Boundary evidence learning should therefore optimize structured quality criteria such as Rand Error or Variation of Information. We present the first structured learning scheme using a structured loss function; and we introduce a new hierarchical scheme that allows to approximately solve the NP hard prediction problem even for huge volume images. The value of these contributions is demonstrated on two challenging neural circuit reconstruction problems in serial sectioning electron microscopic images with billions of voxels. Our contributions lead to a partitioning quality that improves over the current state of the art.
Year
DOI
Venue
2013
10.1007/978-3-642-40763-5_52
Lecture Notes in Computer Science
Field
DocType
Volume
Voxel,Pattern recognition,Computer science,Segmentation,Structured prediction,Variation of information,Artificial intelligence,Cluster analysis,Merge (version control),Random forest
Conference
8150
Issue
ISSN
Citations 
Pt 2
0302-9743
6
PageRank 
References 
Authors
0.51
17
5
Name
Order
Citations
PageRank
Thorben Kroeger11296.37
Shawn Mikula29111.51
Winfried Denk326130.04
Ullrich Koethe424922.37
Fred A. Hamprecht596276.24