Title
Solving the DNA fragment assembly problem efficiently using iterative optimization with evolved hypermutations
Abstract
The paper presents a successful application of an evolutionary based iterative optimization method called Prototype Optimization with Evolved Improvement Steps (POEMS) to the DNA fragment assembly problem. The DNA fragment assembly problem, known to be NP-hard, is of great importance as it constitutes an important step in the genome project. The POEMS is an iterative algorithm that employs an evolutionary algorithm for exploration of the current solution's neighborhood in each iteration of the optimization process. Experiments show that the proposed POEMS approach performs very well and generates better results than those generated by other state-of-the-art methods.
Year
DOI
Venue
2010
10.1145/1830483.1830522
GECCO
Keywords
Field
DocType
iterative optimization method,better result,dna fragment assembly problem,proposed poems approach,iterative algorithm,evolutionary algorithm,prototype optimization,evolved improvement,current solution,optimization process,dna fragmentation,evolutionary algorithms
Mathematical optimization,Genome project,Evolutionary algorithm,Iterative method,Computer science,Algorithm
Conference
Citations 
PageRank 
References 
7
0.53
7
Authors
3
Name
Order
Citations
PageRank
Jiří Kubalik1142.57
Petr Buryan292.18
Libor Wagner370.53