Title
Virtual microscopy of brain tissue
Abstract
Virtual microscopy of brain tissue is demonstrated in a prototype automated system for the parallel tracing of neurons and their connections. The software system (1) incorporates heuristics for tissue feature extraction, (2) demonstrates dendritic arbor and fiber pathway reconstruction, and (3) frames a finite element model of the environment in which these neurons grow and interconnect. The technology will enable the collection of an extensive database of measured neurons, leading to an enlarged knowledge base of neuron morphological models. While our work is directed to neuron and fiber tracing in brain tissue, it is applicable to other similar tissues, for instance, the reconstruction of blood vessels or bronchioles (Barillot et al., Comput. Graphics Appl. 5 (1985) 13-19). (C) 1999 Published by Elsevier Science B.V. All rights reserved.
Year
DOI
Venue
1999
10.1016/S0925-2312(99)00094-6
NEUROCOMPUTING
Keywords
Field
DocType
virtual microscopy,neuron tracing,3D reconstruction,finite element brain
Biomedical engineering,Graphics,Pattern recognition,Computer science,Virtual microscopy,Feature extraction,Artificial intelligence,Neuron,Tracing,Brain tissue,3D reconstruction
Journal
Volume
ISSN
Citations 
26-7
0925-2312
5
PageRank 
References 
Authors
9.32
2
2
Name
Order
Citations
PageRank
brent p burton1910.27
Bruce H. McCormick2134184.45