Title
Early age-related macular degeneration detection by focal biologically inspired feature
Abstract
Age-related macular degeneration (AMD) is a leading cause of vision loss. The presence of drusen are often associated to AMD. Drusen are tiny yellowish-white extracellular buildup present around the macular region of the retina. Clinically, ophthalmologists examine the area around the macula to determine the presence and severity of drusen. However, manual identification and recognition of drusen is subjective, time consuming and expensive. To reduce manual workload and facilitate large-scale early AMD screening, it is essential to detect drusen automatically. In this paper, we propose to use biologically inspired features (BIF) for the purpose of AMD detection. The optic disc and macula are detected to determine a focal region around macula for feature extraction. The extracted features are then classified using support vector machines (SVM). Our experimental results, tested on 350 images, demonstrate that the biologically inspired features from the focal region is effective for drusen detection with a sensitivity of 86.3% and specificity of 91.9%. The results of our proposed approach can be used to reduce workload of ophthalmologists and diagnosis cost.
Year
DOI
Venue
2012
10.1109/ICIP.2012.6467482
ICIP
Keywords
Field
DocType
eye,tiny yellowish-white extracellular buildup,macular region,retinal image,optic disc,svm,retina,biologically inspired feature,large-scale early amd screening,vision loss,feature extraction,image classification,drusen severity,focal region,vision defects,drusen detection,age-related macular degeneration detection,support vector machines,medical image processing,amd detection
Computer vision,Pattern recognition,Computer science,Retina,Support vector machine,Drusen,Feature extraction,Optic disc,Artificial intelligence,Macular degeneration,Contextual image classification
Conference
ISSN
ISBN
Citations 
1522-4880 E-ISBN : 978-1-4673-2532-5
978-1-4673-2532-5
10
PageRank 
References 
Authors
0.64
11
8
Name
Order
Citations
PageRank
Jun Cheng121420.65
Damon Wing Kee Wong243437.78
Xiangang Cheng3556.96
Jiang Liu4406.00
Ngan Meng Tan517515.21
Mayuri Bhargava6181.61
Chui Ming Gemmy Cheung7181.61
Tien Yin Wong838938.10