Paper Info
Title
SPRING: a tool for the analysis of genome rearrangement using reversals and block-interchanges.
Abstract
SPRING( http://algorithm.cs.nthu.edu.tw/tools/SPRING/)is a tool for the analysis of genome rearrangement between two chromosomal genomes using reversals and/ or block- interchanges. SPRING takes two ormore chromosomes as its input and then computes a minimum series of reversals and/ or block-interchanges between any two input chromosomes for transforming one chromosome into another. The input of SPRING can be either bacterial- size sequences or gene/ landmark orders. If the input is a set of chromosomal sequences then the SPRING will automatically search for identical landmarks, which are homologous/ conserved regions shared by all input sequences. In particular, SPRING also computes the breakpoint distance between any pair of two chromosomes, which can be used to compare with the rearrangement distance to confirm whether they are correlated or not. In addition, SPRING shows phylogenetic trees that are reconstructed based on the rearrangement and breakpoint distance matrixes.
Year
DOI
Venue
2006
10.1093/nar/gkl169
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
phylogenetic tree,distance matrix
Genome,Phylogenetic tree,Chromosome,Biology,Chromosomal inversion,Genome rearrangement,Genomics,Breakpoint,Phylogenetics,Genetics
Journal
Volume
Issue
ISSN
34
Web-Server-Issue
0305-1048
Citations 
PageRank 
References 
9
1.01
11
Authors
4
Name
Order
Citations
PageRank
Ying Chih Lin1665.08
Chin Lung Lu242334.59
Ying-Chuan Liu391.35
Chuan Yi Tang470479.25