Title
Multiple Sequence Alignments With Regular Expression Constraints On A Cloud Service System
Abstract
Multiple sequence alignments with constraints are of priority concern in computational biology. Constrained sequence alignment incorporates the domain knowledge of biologists into sequence alignments such that the user-specified residues/ segments are aligned together according to the alignment results. A series of constrained multiple sequence alignment tools have been developed in relevant literatures in the recent decade. GPUREMuSiC is the most advanced method with the regular expression constraints, in which graphics processing units (GPUs) with CUDA are used. GPU-REMuSiC can achieve a speedup ratio of 29x for overall computation time based on the experimental results. However, the execution environment of GPU-REMuSiC must be constructed; it is a threshold for biologists to set up it. Therefore, this work presents an intuitive friendly user interface of GPU-REMuSiC for the potential cloud server with GPUs, called Cloud GPU-REMuSiC. Implementing the user interface via a network allows us to transmit the input data to a remote server without a complex cumbersome setting in a local host. Finally, the alignment results can be obtained from a remote cloud server with GPUs. Cloud GPU-REMuSiC is highly promising as an online application that is accessible without time or location constraints.
Year
DOI
Venue
2013
10.4018/jghpc.2013070105
INTERNATIONAL JOURNAL OF GRID AND HIGH PERFORMANCE COMPUTING
Keywords
Field
DocType
Cloud Computing, CUDA, Dynamic Programming, Graphics Processing Units (GPUs), Multiple Sequence Alignments, Parallel Processing, Regular Expression, User Interface
Graphics,Regular expression,Domain knowledge,CUDA,Computer science,Multiple sequence alignment,User interface,Speedup,Cloud computing,Distributed computing
Journal
Volume
Issue
ISSN
5
3
1938-0259
Citations 
PageRank 
References 
0
0.34
26
Authors
4
Name
Order
Citations
PageRank
Yu-Shiang Lin18713.27
Chun-yuan Lin210621.61
Hsiao-Chieh Chi311.42
Yeh-Ching Chung498397.16