Name
Abstract | ||
|---|---|---|
Background There is a large amount of inconsistency in gene structure annotations of bacterial strains. This inconsistency is a frustrating
impedance to effective comparative genomic analysis of bacterial strains in promising applications such as gaining insights
into bacterial drug resistance.
Results Here, we propose CAMBer as an approach to support comparative analysis of multiple bacterial strains. CAMBer produces what
we called multigene families. Each multigene family reveals genes that are in one-to-one correspondence in the bacterial strains,
thereby permitting their annotations to be integrated. We present results of our method applied to three human pathogens:
Escherichia coli, Mycobacterium tuberculosis and Staphylococcus aureus.
Conclusions As a result, more accurate and more comprehensive annotations of the bacterial strains can be produced. |
Year | DOI | Venue |
|---|---|---|
2010 | 10.1186/1471-2164-12-S2-S6 | Bioinformatics and Biomedicine |
Keywords | Field | DocType |
comparative genomics,microarrays,comparative analysis,computer graphics,escherichia coli,proteomics,gene structure,computational biology | Comparative genomic analysis,Biology,Drug resistance,Bioinformatics,Genetics,DNA microarray,Escherichia coli | Conference |
Volume | Issue | ISSN |
12 | S2 | 1471-2164 |
ISBN | Citations | PageRank |
978-1-4244-8307-5 | 5 | 0.81 |
References | Authors | |
3 | 3 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Michal Wozniak | 1 | 764 | 83.90 |
| Limsoon Wong | 2 | 3628 | 638.37 |
| Jerzy Tiuryn | 3 | 1210 | 126.00 |