Title
Simulation of Transmembrane Potential Propagation in Three-Dimensional Bidomain Cardiac Tissue
Abstract
The transmembrane potential propagation in a slab of three-dimensional cardiac tissue stimulated by an unipolar extracellular shock on epicardium is simulated for a full cycle of action potential duration. A semi-implicit method is implemented for the first time on a single cpu workstation to numerically calculate the transmembrane potential field in a three-dimensional bidomain incorporating rotational anisotropy and active ionic currents. A fast preconditioned Krylov subspace iterative method is found to efficiently solve the huge number of linear equations at each time step. It is suggested that this methodology can be used to simulate transmembrane potential in cardiac tissue for seconds after an electric defibrillation shock, which requires long time three-dimensional bidomain simulation.
Year
DOI
Venue
2006
10.1109/IMSCCS.2006.125
IMSCCS (1)
Keywords
Field
DocType
transmembrane potential propagation,three-dimensional bidomain cardiac tissue,transmembrane potential,three-dimensional cardiac tissue,long time,transmembrane potential field,action potential duration,time step,three-dimensional bidomain simulation,cardiac tissue,three-dimensional bidomain,mathematical model,computer science,solid modeling,extracellular,iteration method,computer simulation,iterative methods,krylov subspace,space technology,linear equations,computational modeling,linear equation,three dimensional
Krylov subspace,Linear equation,Mathematical optimization,Membrane potential,Anisotropy,Numerical models,Iterative method,Computer science,Action potential duration,Mechanics
Conference
ISBN
Citations 
PageRank 
0-7695-2581-4-01
1
0.55
References 
Authors
2
3
Name
Order
Citations
PageRank
yin zhou1437.35
Peter Jung2237.50
Chaoyan Zhu341.04