Name
Title | ||
|---|---|---|
Multi-program approach for simulating recorded extracellular signals generated by neurons coupled to microelectrode arrays |
Abstract | ||
|---|---|---|
Purpose of this paper is to present a new tool for characterizing the coupling between neurons and micro-electrode arrays (MEAs), based on a multi-program simulation approach. As a result, recorded extracellular signals generated by networks of neurons coupled to MEAs can be simulated with a combined interaction of modified and developed models implemented in simulation programs such as Spice, Neuron, and Matlab. The proposed approach allows an efficient simulation of the behaviour of the specific neuron-electrode junctions and the simulation of synaptically connected neuronal populations. Models of the neuron, synapse, microelectrode and neuron-electrode junction are presented and comparison between simulation results and multi-site extracellular recordings are shown. |
Year | DOI | Venue |
|---|---|---|
2007 | 10.1016/j.neucom.2006.09.008 | Neurocomputing |
Keywords | Field | DocType |
simulation program,simulation result,multi-program approach,neuron-electrode junction,extracellular signal recording,efficient simulation,recorded extracellular,neuron-microelectrode junction simulation,multi-site extracellular recording,microelectrode model,specific neuron-electrode junction,neuron model,multi-program simulation approach,combined interaction,adhesion conditions,population model,microelectrode array | Synapse,Biological neuron model,MATLAB,Coupling,Biological system,Pattern recognition,Spice,Artificial intelligence,Local field potential,Neuron,Microelectrode,Mathematics | Journal |
Volume | Issue | ISSN |
70 | 13-15 | Neurocomputing |
Citations | PageRank | References |
6 | 0.71 | 4 |
Authors | ||
3 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Paolo Massobrio | 1 | 22 | 5.21 |
| Giuseppe Massobrio | 2 | 8 | 2.16 |
| S Martinoia | 3 | 158 | 20.68 |