Title
On the reduction of errors in DNA computation.
Abstract
In this paper, we discuss techniques for reducing errors in DNA computation. We investigate several methods for achieving acceptable overall error rates for a computation using basic operations that are error prone. We analyze a single essential biotechnology, sequence-specific separation, and show that separation errors theoretically can be reduced to tolerable levels by invoking a tradeoff between time, space, and error rates at the level of algorithm design, These tradeoffs do not depend upon improvement of the underlying biotechnology which implements the separation step. We outline several specific ways in which error reduction can be done and present numerical calculations of their performance.
Year
DOI
Venue
1999
10.1089/cmb.1999.6.65
JOURNAL OF COMPUTATIONAL BIOLOGY
Keywords
Field
DocType
DNA computations,error reduction,errors,molecular computation
Algorithm design,Computer science,Algorithm,Computation
Journal
Volume
Issue
ISSN
6.0
1
1066-5277
Citations 
PageRank 
References 
8
2.80
9
Authors
2
Name
Order
Citations
PageRank
Sam T. Roweis14556497.42
Erik Winfree21314157.04