Paper Info
Title
iview: an interactive WebGL visualizer for protein-ligand complex.
Abstract
Visualization of protein-ligand complex plays an important role in elaborating protein-ligand interactions and aiding novel drug design. Most existing web visualizers either rely on slow software rendering, or lack virtual reality support. The vital feature of macromolecular surface construction is also unavailable.We have developed iview, an easy-to-use interactive WebGL visualizer of protein-ligand complex. It exploits hardware acceleration rather than software rendering. It features three special effects in virtual reality settings, namely anaglyph, parallax barrier and oculus rift, resulting in visually appealing identification of intermolecular interactions. It supports four surface representations including Van der Waals surface, solvent excluded surface, solvent accessible surface and molecular surface. Moreover, based on the feature-rich version of iview, we have also developed a neat and tailor-made version specifically for our istar web platform for protein-ligand docking purpose. This demonstrates the excellent portability of iview.Using innovative 3D techniques, we provide a user friendly visualizer that is not intended to compete with professional visualizers, but to enable easy accessibility and platform independence.
Year
DOI
Venue
2014
10.1186/1471-2105-15-56
BMC Bioinformatics
Keywords
Field
DocType
molecular docking,structural bioinformatics,visualization,algorithms,microarrays,protein binding,proteins,internet,computational biology,computer graphics,ligands,bioinformatics
Structural bioinformatics,Protein–ligand complex,Virtual reality,Computer science,Visualization,Software,Bioinformatics,Software rendering,Computer graphics,The Internet
Journal
Volume
Issue
ISSN
15
1
1471-2105
Citations 
PageRank 
References 
23
0.98
12
Authors
4
Name
Order
Citations
PageRank
Hongjian Li1646.26
Kwong-Sak Leung21887205.58
Takanori Nakane3230.98
Man Hon Wong4814233.13