Title
Metamodeling integration architecture for open biomedical ontologies: the GO extensions' case study
Abstract
New technologies used in biology are generating huge quantities of data; up to two petabytes of overall data are to be expected by the end of the decade. Modern biology also has to deal with multitude of information representations that are driven by the continuous evolution of biological knowledge. Conceptual modeling allows layered descriptions whose abstractions are rather stable while their concrete descriptions may evolve: formal ontologies versus domain ontologies, metamodels versus models, etc. In this paper we introduce an incremental integration methodology that is based on the Open Biomedical Ontology (OBO) umbrella. The proof of concept for our methodology is carried out using the Gene Ontology's (GO) case study in which GO extensions are viewed as manifestations of the domain knowledge evolution. Based on this conceptual foundation, we present a metamodeling architecture that encompasses metamodels and models of GO, as well as those of GO extensions. Our architecture can be used for ensuring semantical quality of biological knowledge integration.
Year
Venue
Keywords
2007
ER (Tutorials, Posters, Panels & Industrial Contributions)
domain ontology,continuous evolution,gene ontology,biological knowledge integration,open biomedical ontology,domain knowledge evolution,metamodeling integration architecture,conceptual foundation,encompasses metamodels,case study,conceptual modeling,biological knowledge,knowledge integration,open biomedical ontologies,ontology,proof of concept,conceptual model
Field
DocType
Citations 
Ontology (information science),Ontology-based data integration,Data mining,Knowledge integration,Process ontology,Domain knowledge,Computer science,Open Biomedical Ontologies,Upper ontology,Metamodeling
Conference
0
PageRank 
References 
Authors
0.34
15
8