Title
A minimal model of tumor growth inhibition in combination regimens under the hypothesis of no interaction between drugs.
Abstract
One important issue in the preclinical development of an anticancer drug is the assessment of the compound under investigation when administered in combination with other drugs. Several experiments are routinely conducted in xenograft mice to evaluate if drugs interact or not. Experimental data are generally qualitatively analyzed on empirical basis. The ability of deriving from single drug experi...
Year
DOI
Venue
2012
10.1109/TBME.2012.2197680
IEEE Transactions on Biomedical Engineering
Keywords
Field
DocType
Drugs,Tumors,Mathematical model,Compounds,Probability density function,Equations,Mice
Computer science,Pharmacology,Minimal model,Electronic engineering,Growth inhibition,Computational biology,Drug,Drug administration
Journal
Volume
Issue
ISSN
59
8
0018-9294
Citations 
PageRank 
References 
0
0.34
1
Authors
5
Name
Order
Citations
PageRank
P Magni143838.77
Nadia Terranova220.81
Francesca Del Bene310.75
Massimiliano Germani410.75
Giuseppe De Nicolao573876.26