Title | ||
---|---|---|
A minimal model of tumor growth inhibition in combination regimens under the hypothesis of no interaction between drugs. |
Abstract | ||
---|---|---|
One important issue in the preclinical development of an anticancer drug is the assessment of the compound under investigation when administered in combination with other drugs. Several experiments are routinely conducted in xenograft mice to evaluate if drugs interact or not. Experimental data are generally qualitatively analyzed on empirical basis. The ability of deriving from single drug experi... |
Year | DOI | Venue |
---|---|---|
2012 | 10.1109/TBME.2012.2197680 | IEEE Transactions on Biomedical Engineering |
Keywords | Field | DocType |
Drugs,Tumors,Mathematical model,Compounds,Probability density function,Equations,Mice | Computer science,Pharmacology,Minimal model,Electronic engineering,Growth inhibition,Computational biology,Drug,Drug administration | Journal |
Volume | Issue | ISSN |
59 | 8 | 0018-9294 |
Citations | PageRank | References |
0 | 0.34 | 1 |
Authors | ||
5 |
Name | Order | Citations | PageRank |
---|---|---|---|
P Magni | 1 | 438 | 38.77 |
Nadia Terranova | 2 | 2 | 0.81 |
Francesca Del Bene | 3 | 1 | 0.75 |
Massimiliano Germani | 4 | 1 | 0.75 |
Giuseppe De Nicolao | 5 | 738 | 76.26 |