Abstract | ||
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MODalign is an interactive web-based tool aimed at helping protein structure modelers to inspect and manually modify the alignment between the sequences of a target protein and of its template(s). It interactively computes, displays and, upon modification of the target-template alignment, updates the multiple sequence alignments of the two protein families, their conservation score, secondary structure and solvent accessibility values, and local quality scores of the implied three-dimensional model(s). Although it has been designed to simplify the target-template alignment step in modeling, it is suitable for all cases where a sequence alignment needs to be inspected in the context of other biological information.Freely available on the web at http://modorama.biocomputing.it/modalign. Website implemented in HTML and JavaScript with all major browsers supported.jan.kosinski@uniroma1.it. |
Year | DOI | Venue |
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2012 | 10.1093/bioinformatics/bts070 | Bioinformatics |
Keywords | Field | DocType |
protein family,target-template alignment,sequence alignment,multiple sequence alignment,biological information,protein structure modeler,target-template alignment step,secondary structure,target protein,conservation score,internet,proteins | Sequence alignment,Data mining,Protein family,World Wide Web,Computer science,Software,Bioinformatics,Protein secondary structure,The Internet,JavaScript,Protein structure | Journal |
Volume | Issue | ISSN |
28 | 7 | 1367-4811 |
Citations | PageRank | References |
3 | 0.45 | 3 |
Authors | ||
5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Alessandro Barbato | 1 | 19 | 1.93 |
Pascal Benkert | 2 | 69 | 4.90 |
Torsten Schwede | 3 | 500 | 42.56 |
Anna Tramontano | 4 | 191 | 14.13 |
Jan Kosinski | 5 | 31 | 1.72 |