Title
Improving your target-template alignment with MODalign.
Abstract
MODalign is an interactive web-based tool aimed at helping protein structure modelers to inspect and manually modify the alignment between the sequences of a target protein and of its template(s). It interactively computes, displays and, upon modification of the target-template alignment, updates the multiple sequence alignments of the two protein families, their conservation score, secondary structure and solvent accessibility values, and local quality scores of the implied three-dimensional model(s). Although it has been designed to simplify the target-template alignment step in modeling, it is suitable for all cases where a sequence alignment needs to be inspected in the context of other biological information.Freely available on the web at http://modorama.biocomputing.it/modalign. Website implemented in HTML and JavaScript with all major browsers supported.jan.kosinski@uniroma1.it.
Year
DOI
Venue
2012
10.1093/bioinformatics/bts070
Bioinformatics
Keywords
Field
DocType
protein family,target-template alignment,sequence alignment,multiple sequence alignment,biological information,protein structure modeler,target-template alignment step,secondary structure,target protein,conservation score,internet,proteins
Sequence alignment,Data mining,Protein family,World Wide Web,Computer science,Software,Bioinformatics,Protein secondary structure,The Internet,JavaScript,Protein structure
Journal
Volume
Issue
ISSN
28
7
1367-4811
Citations 
PageRank 
References 
3
0.45
3
Authors
5
Name
Order
Citations
PageRank
Alessandro Barbato1191.93
Pascal Benkert2694.90
Torsten Schwede350042.56
Anna Tramontano419114.13
Jan Kosinski5311.72