Paper Info
Title
Organelle DB: a cross-species database of protein localization and function.
Abstract
To efficiently utilize the growing body of available protein localization data, we have developed Organelle DB, a web-accessible database cataloging more than 25000 proteins from nearly 60 organelles, subcellular structures and protein complexes in 154 organisms spanning the eukaryotic kingdom. Organelle DB is the first on-line resource devoted to the identification and presentation of eukaryotic proteins localized to organelles and subcellular structures. As such, Organelle DB is a strong resource of data from the human proteome as well as from the major model organisms Saccharomyces cerevisiae, Arabidopsis thaliana, Drosophila melanogaster, Caenorhabditis elegans and Mus musculus. In particular, Organelle DB is a central repository of yeast data, incorporating results-and actual fluorescent images-from ongoing large-scale studies of protein localization in S.cerevisiae. Each protein in Organelle DB is presented with its sequence and, as available, a detailed description of its function; functions were extracted from relevant model organism databases, and links to these databases are provided within Organelle DB. To facilitate data interoperability, we have annotated all protein localizations using vocabulary from the Gene Ontology consortium. We also welcome new data for inclusion in Organelle DB, which may be freely accessed at http://organelledb.Isi.umich.edu.
Year
DOI
Venue
2005
10.1093/nar/gki071
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
fluorescence imaging,protein complex,protein localization,web accessibility
Human proteome project,Drosophila Protein,Biology,Caenorhabditis elegans,Cell biology,Protein subcellular localization prediction,Organelle,Saccharomyces cerevisiae,Model organism,Drosophila melanogaster,Database
Journal
Volume
Issue
ISSN
33
Database issue
0305-1048
Citations 
PageRank 
References 
10
0.91
5
Authors
2
Name
Order
Citations
PageRank
Nuwee Wiwatwattana136717.50
Anuj Kumar2151.43