Title
Identifying multiple alignment regions satisfying simple formulas and patterns.
Abstract
When studying multiple alignments of genomic sequences one frequently aims to locate and count regions which satisfy a set of constraints. These regions may be putatively functional, but researchers may also be interested in quantifying the frequency of occurrences of certain patterns.We have developed a program that applies simple formulas and pattern specifications to multiple alignments, reporting the positions and counts of conforming regions. As an example, we have navigated a 15-species alignment of the CAV2-CAV1 region and outlined some findings regarding PPARgamma binding sites.Our software and the accompanying documentation can be obtained at no charge by contacting the authors. It can also be accessed at http://ranger.uta.edu/~nick/compgen
Year
DOI
Venue
2004
10.1093/bioinformatics/bth196
Bioinformatics
Keywords
Field
DocType
pattern specification,accompanying documentation,15-species alignment,binding site,multiple alignment region,count region,certain pattern,simple formula,multiple alignment,satisfiability,genome sequence
Data mining,Computer science,Software,Bioinformatics,Documentation,Multiple sequence alignment
Journal
Volume
Issue
ISSN
20
13
1367-4803
Citations 
PageRank 
References 
0
0.34
0
Authors
2
Name
Order
Citations
PageRank
Nikola Stojanovic1398.53
Ken Dewar221.55