Title
Bayesian second-level analysis of functional magnetic resonance images.
Abstract
We propose a new method for the second-level analysis of functional MRI data based on Bayesian statistics. Our method does not require a computationally costly Bayesian model on the first level of analysis. Rather, modeling for single subjects is realized by means of the commonly applied General Linear Model. On the basis of the resulting parameter estimates for single subjects we calculate posterior probability maps and maps of the effect size for effects of interest in groups of subjects. A comparison of this method with the conventional analysis based on t statistics shows that the new approach is more robust against outliers. Moreover, our method overcomes some of the severe problems of null hypothesis significance tests such as the need to correct for multiple comparisons and facilitates inferences which are hard to formulate in terms of classical inferences.
Year
DOI
Venue
2003
10.1016/S1053-8119(03)00443-9
NeuroImage
Keywords
DocType
Volume
parameter estimation,bayesian statistics,multiple comparisons,null hypothesis significance testing,effect size,general linear model,posterior probability,bayesian model
Journal
20
Issue
ISSN
Citations 
2
1053-8119
19
PageRank 
References 
Authors
1.81
6
2
Name
Order
Citations
PageRank
Jane Neumann112213.15
Gabriele Lohmann235640.09