Title
Comparative evaluation of support vector machines for computer aided diagnosis of lung cancer in CT based on a multi-dimensional data set.
Abstract
Lung cancer is one of the most common forms of cancer resulting in over a million deaths per year worldwide. In this paper, the usage of support vector machine (SVM) classification for lung cancer is investigated, presenting a systematic quantitative evaluation against Boosting, Decision trees, k-nearest neighbor, LASSO regressions, neural networks and random forests. A large database of 5984 regions of interest (ROIs) and 488 input features (including textural features, patient characteristics, and morphological features) were used to train the classifiers and evaluate for their performance. The evaluation for classifiers' performance was based on a tenfold cross validation framework, receiver operating characteristic curve (ROC), and Matthews correlation coefficient. Area under curve (AUC) of SVM, Boosting, Decision trees, k-nearest neighbor, LASSO, neural networks, random forests were 0.94, 0.86, 0.73, 0.72, 0.91, 0.92, and 0.85, respectively. It was proved that SVM classification offered significantly increased classification performance compared to the reference methods. This scheme may be used as an auxiliary tool to differentiate between benign and malignant SPNs of CT images in future.
Year
DOI
Venue
2013
10.1016/j.cmpb.2013.04.016
Computer Methods and Programs in Biomedicine
Keywords
Field
DocType
characteristic curve,neural network,lung cancer,random forest,solitary pulmonary nodule,support vector machine,curvelet,lasso regression,k-nearest neighbor,systematic quantitative evaluation,texture extraction,classification performance,decision tree,multi-dimensional data,comparative evaluation,ct image,svm classification
Decision tree,Receiver operating characteristic,Pattern recognition,Computer science,Computer-aided diagnosis,Support vector machine,Lasso (statistics),Artificial intelligence,Boosting (machine learning),Random forest,Cross-validation,Machine learning
Journal
Volume
Issue
ISSN
111
2
1872-7565
Citations 
PageRank 
References 
16
0.86
18
Authors
9
Name
Order
Citations
PageRank
Tao Sun116816.47
Jingjing Wang2160.86
Xia Li3160.86
Pingxin Lv4251.46
Fen Liu5160.86
Yanxia Luo6160.86
Qi Gao7160.86
Huiping Zhu8160.86
Xiuhua Guo9273.21