Title
Manifold diffusion for exophytic kidney lesion detection on non-contrast CT images.
Abstract
Kidney lesions are important extracolonic findings at computed tomographic colonography (CTC). However, kidney lesion detection on non-contrast CTC images poses significant challenges due to low image contrast with surrounding tissues. In this paper, we treat the kidney surface as manifolds in Riemannian space and present an intrinsic manifold diffusion approach to identify lesion-caused protrusion while simultaneously removing geometrical noise on the manifolds. Exophytic lesions (those that deform the kidney surface) are detected by searching for surface points with local maximum diffusion response and using the normalized cut algorithm to extract them. Moreover, multi-scale diffusion response is a discriminative feature descriptor for the subsequent classification to reduce false positives. We validated the proposed method and compared it with a baseline method using shape index on CTC datasets from 49 patients. Free-response receiver operating characteristic analysis showed that at 7 false positives, the proposed method achieved 87% sensitivity while the baseline method achieved only 22% sensitivity. The proposed method showed far fewer false positives compared with the baseline method which makes it feasible for clinical practice.
Year
DOI
Venue
2013
10.1007/978-3-642-40811-3_43
Lecture Notes in Computer Science
Keywords
Field
DocType
Kidney lesion detection,computed tomographic colonography,manifold diffusion,extracolonic finding,Riemannian manifold
Computer vision,Feature descriptor,Kidney lesion,Shape index,Pattern recognition,Clinical Practice,Computed Tomographic Colonography,Artificial intelligence,Discriminative model,Manifold,Mathematics,False positive paradox
Conference
Volume
Issue
ISSN
8149
Pt 1
0302-9743
Citations 
PageRank 
References 
1
0.35
10
Authors
5
Name
Order
Citations
PageRank
Jianfei Liu18112.98
Shijun Wang223922.83
Jianhua Yao31135110.49
Marius George Linguraru436248.94
Ronald M Summers510.35