Title
Improved recognition of figures containing fluorescence microscope images in online journal articles using graphical models.
Abstract
There is extensive interest in automating the collection, organization and analysis of biological data. Data in the form of images in online literature present special challenges for such efforts. The first steps in understanding the contents of a figure are decomposing it into panels and determining the type of each panel. In biological literature, panel types include many kinds of images collected by different techniques, such as photographs of gels or images from microscopes. We have previously described the SLIF system (http://slif.cbi.cmu.edu) that identifies panels containing fluorescence microscope images among figures in online journal articles as a prelude to further analysis of the subcellular patterns in such images. This system contains a pretrained classifier that uses image features to assign a type (class) to each separate panel. However, the types of panels in a figure are often correlated, so that we can consider the class of a panel to be dependent not only on its own features but also on the types of the other panels in a figure.In this article, we introduce the use of a type of probabilistic graphical model, a factor graph, to represent the structured information about the images in a figure, and permit more robust and accurate inference about their types. We obtain significant improvement over results for considering panels separately.The code and data used for the experiments described here are available from http://murphylab.web.cmu.edu/software.
Year
DOI
Venue
2008
10.1093/bioinformatics/btm561
Bioinformatics
Keywords
Field
DocType
online literature,fluorescence microscope image,panel type,biological data,extensive interest,different technique,graphical model,separate panel,slif system,biological literature,improved recognition,accurate inference,online journal article,factor graph,bioinformatics,image features,fluorescence
Factor graph,Biological data,Feature (computer vision),Computer science,Software,Graphical model,Bioinformatics,Probabilistic logic,Classifier (linguistics),Computer graphics
Journal
Volume
Issue
ISSN
24
4
1367-4811
Citations 
PageRank 
References 
15
0.90
13
Authors
2
Name
Order
Citations
PageRank
Yuntao Qian159754.17
Robert F Murphy285178.19