Title
Spatial Information and Boolean Genetic Regulatory Networks
Abstract
Modelling frameworks for biological networks are used to reason on the models and their properties. One of the main problems with such modelling frameworks is to determine the dynamics of gene regulatory networks (GRN). Recently, it has been observed in in vivo experiments and in genomic and transcriptomic studies, that spatial information are useful to better understand both the mechanisms and the dynamics of GRN. In this paper we propose to extend the modelling framework of R. Thomas in order to introduce such spatial information between genes, and we will show how these further informations allow us to restrict the number of dynamics to consider.
Year
DOI
Venue
2009
10.1007/978-3-642-00727-9_26
Lecture Notes in Computer Science
Keywords
Field
DocType
biological network,transcriptomic study,vivo experiment,gene regulatory network,spatial information,boolean genetic regulatory networks,main problem,modelling framework
Spatial analysis,Biological network,Computer science,Artificial intelligence,Bioinformatics,Gene regulatory network,Machine learning
Conference
Volume
ISSN
Citations 
5462
0302-9743
0
PageRank 
References 
Authors
0.34
2
6
Name
Order
Citations
PageRank
Matthieu Manceny173.55
Marc Aiguier29814.95
Pascale Gall3132.08
Joan Hérisson4376.62
Ivan Junier5111.72
François Képès6478.97