Title
GenePath: from mutations to genetic networks and back.
Abstract
GenePath is a web-based application for the analysis of mutant-based experiments and synthesis of genetic networks. Here, we introduce GenePath and describe a number of new approaches, including conflict resolution, handling cyclic pathways, confidence level assignment, what-if analysis and new experiment proposal. We illustrate the key concepts using data from a study of adhesion genes in Dictyostelium discoideum and show that GenePath discovered genetic interactions that were ignored in the original publication. GenePath is available at http://www.genepath.org/genepath2.
Year
DOI
Venue
2005
10.1093/nar/gki426
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
genes,internet,web based applications,confidence level,mutation,computational biology,genomics
Biology,Genomics,Genetics
Journal
Volume
Issue
ISSN
33
SUPnan
0305-1048
Citations 
PageRank 
References 
9
0.71
3
Authors
4
Name
Order
Citations
PageRank
Peter Juvan1454.10
Janez Demšar24276156.75
Gad Shaulsky312011.98
Blaz Zupan41277102.37