Paper Info
Title
Studying the capability of different cancer hallmarks to initiate tumor growth using a cellular automaton simulation. Application in a cancer stem cell context.
Abstract
We used a cellular automaton model for cancer growth simulation at cellular level, based on the presence of different cancer hallmarks acquired by the cells. The presence of the hallmarks in each of the cells determines cell mitotic and apoptotic behaviors. Depending on the presence of the different hallmarks and some associated parameters of the hallmarks, the system can evolve to different dynamics. We used the cellular automaton model to inspect the capability of different hallmarks to generate tumor growth in different conditions, using this study in a cancer stem cell context to analyze the capability of the hallmarks to tumor regrowth in different circumstances.
Year
DOI
Venue
2014
10.1016/j.biosystems.2013.11.001
Biosystems
Keywords
Field
DocType
Cellular automata,Cellular behavior,Cancer growth modeling,Cancer stem cells
Carcinogenesis,Cellular automaton,Nanotechnology,Mitosis,Biology,Cancer stem cell,Cell,Computational biology,Genetics,Cancer
Journal
Volume
ISSN
Citations 
115
0303-2647
2
PageRank 
References 
Authors
0.42
4
2
Name
Order
Citations
PageRank
Ángel Monteagudo1284.18
José Santos29714.77