Paper Info
Title
Micro-Injection System for Localized Drug Delivery Using Embedded Solid Chemical Propellant
Abstract
This paper presents a novel micro-injection system for localized drug delivery using embedded solid chemical propellant, azobisisobutyronitrile (AIBN). This system consists of in-plane type of microneedles, a drug reservoir, a chemical fluid source, a chemical fluid source chamber, and a microheater. The AIBN decomposes and produces nitrogen gas and a free radical at about 70. Using this phenomenon, the AIBN on the microheater generates nitrogen gas by supplying an electrical power, and then the generated nitrogen gas injects a drug in the drug reservoir through the micro channel buried at the microneedles. This micro-injection system injects 2.29 ~ 2.9 µl blue ink during about 6 seconds by supplying 30.4 V and 164 mA. This novel injection system is expected to be applicable to the highly precise biological equipments. Key words: micro-injection, drug delivery, azobisisobutyronitrile (AIBN), microneedles, microheater
Year
DOI
Venue
2007
10.1109/FBIT.2007.110
FBIT
Keywords
Field
DocType
micro-injection system,localized drug delivery,chemical fluid source,chemical fluid source chamber,drug reservoir,nitrogen gas,novel injection system,novel micro-injection system,drug delivery,solid chemical propellant,micro-injection system injects,aibn decomposes,nitrogen,electric power,biomems,microchannel,free radical
Nitrogen,Propellant,Inkwell,Microheater,Chemical engineering,Microchannel,Azobisisobutyronitrile,Drug delivery,Materials science,Drug reservoir
Conference
Citations 
PageRank 
References 
0
0.34
0
Authors
5
Name
Order
Citations
PageRank
Jae-won Ban100.68
Kyo-in Koo234.37
Sunkil Park300.34
Gilsub Kim400.34
Dong-Il Dan Cho5179.99