Paper Info
Title
Effect of fibre orientation optimisation in an electromechanical model of left ventricular contraction in rat
Abstract
Subject-specific, or personalised, modelling is one of the main targets in current cardiac modelling research. The aim of this study is to assess the improvement in predictive power gained by introducing subject-specific fibre models within an electromechanical model of left ventricular contraction in rat. A quantitative comparison of a series of global rule-based fibre models with an image-based locally optimised fibre model was performed. Our results show small difference in the predicted values of ejection fraction, wall thickening and base-to-apex shortening between the fibre models considered. In comparison, much larger differences appear between predicted values and those measured in experimental images. Further study of the constitutive behaviour and architecture of cardiac tissue is required before electromechanical models can fully benefit from the introduction of subject-specific fibres. Additionally, our study shows that, in the current model, an orthotropic description of the tissue is preferable to a transversely isotropic one, for the metrics considered.
Year
DOI
Venue
2013
10.1007/978-3-642-38899-6_6
FIMH
Keywords
Field
DocType
subject-specific fibre,left ventricular contraction,electromechanical model,fibre orientation optimisation,subject-specific fibre model,optimised fibre model,global rule-based fibre model,fibre model,current model,quantitative comparison,current cardiac modelling research,cardiac tissue
Contraction (grammar),Helix angle,Orthotropic material,Fiber,Mechanics,Thickening,Transverse isotropy,Materials science
Conference
Volume
ISSN
Citations 
7945
0302-9743
3
PageRank 
References 
Authors
0.48
5
7
Name
Order
Citations
PageRank
Valentina Carapella151.87
Rafel Bordas2979.82
Pras Pathmanathan311111.77
Jurgen E. Schneider430.82
Peter Kohl593.28
Kevin Burrage631537.67
Vicente Grau717813.55