Name
Abstract | ||
|---|---|---|
The structural genomics of histone tail recognition web server is an open access resource that presents within mini articles all publicly available experimental structures of histone tails in complex with human proteins. Each article is composed of interactive 3D slides that dissect the structural mechanism underlying the recognition of specific sequences and histone marks. A concise text html-linked to interactive graphics guides the reader through the main features of the interaction. This resource can be used to analyze and compare binding modes across multiple histone recognition modules, to evaluate the chemical tractability of binding sites involved in epigenetic signaling and design small molecule inhibitors.http://www.thesgc.org/resources/histone_tails/matthieu.schapira@utoronto.caSupplementary data are available at Bioinformatics online. |
Year | DOI | Venue |
|---|---|---|
2010 | 10.1093/bioinformatics/btq491 | Bioinformatics |
Keywords | Field | DocType |
histone mark,histone tail recognition web,histone tail,multiple histone recognition module,interactive graphics guide,binding site,binding mode,structural genomics,available experimental structure,open access resource,genomics,histones,protein conformation,binding sites | Human proteins,Structural genomics,Histone,Computer science,Genomics,Interactive 3d,Bioinformatics,Web server,Epigenetics,Protein structure | Journal |
Volume | Issue | ISSN |
26 | 20 | 1367-4811 |
Citations | PageRank | References |
1 | 0.44 | 0 |
Authors | ||
9 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Minghua Wang | 1 | 1 | 0.44 |
| Man Wai Mok | 2 | 8 | 0.97 |
| Hong Harper | 3 | 1 | 0.44 |
| Wen Hwa Lee | 4 | 1 | 0.44 |
| Jinrong Min | 5 | 1 | 0.44 |
| Stefan Knapp | 6 | 1 | 0.44 |
| Udo Oppermann | 7 | 1 | 0.44 |
| Brian Marsden | 8 | 1 | 0.44 |
| Matthieu Schapira | 9 | 21 | 4.41 |