Title | ||
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Electron Transfer Mediated Biosensor With Plasma-Polymerized Film Containing Redox Site |
Abstract | ||
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An electron transfer mediated amperometric enzyme biosensor based on a plasma-polymerized thin film of dimethylaminomethylferrocene (DMAMFc) is reported. A nanoscale thin polymer film containing a redox mediator was plasma-deposited directly onto an electrode with physisorbed glucose oxidase (GOD). Since the redox sites were introduced in the vicinity of the reaction centers of GOD, a highly efficient electron transfer system was formed in which almost all the reaction centers of GOD were connected to redox sites-of the polymer matrix. The advantages of this strategy were: no need for prior or further chemical modification of the enzyme molecules, and simplicity of design compared with the use of a conventional polymer matrix. Moreover, the fact that the film deposition was performed using a microfabrication-compatible organic plasma promised great potential for high-throughput production of bioelectronic devices. |
Year | DOI | Venue |
---|---|---|
2006 | 10.1093/ietele/e89-c.12.1781 | IEICE TRANSACTIONS ON ELECTRONICS |
Keywords | Field | DocType |
glucose biosensor electron transfer mediator, plasma polymerization, ferrocene, enzyme | Polymerization,Chemistry,Electron transfer,Biosensor,Plasma,Photochemistry,Redox | Journal |
Volume | Issue | ISSN |
E89C | 12 | 0916-8524 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
2 |
Name | Order | Citations | PageRank |
---|---|---|---|
hitoshi | 1 | 1 | 4.01 |
Hideyuki Uehara | 2 | 54 | 12.14 |