Title
Electron Transfer Mediated Biosensor With Plasma-Polymerized Film Containing Redox Site
Abstract
An electron transfer mediated amperometric enzyme biosensor based on a plasma-polymerized thin film of dimethylaminomethylferrocene (DMAMFc) is reported. A nanoscale thin polymer film containing a redox mediator was plasma-deposited directly onto an electrode with physisorbed glucose oxidase (GOD). Since the redox sites were introduced in the vicinity of the reaction centers of GOD, a highly efficient electron transfer system was formed in which almost all the reaction centers of GOD were connected to redox sites-of the polymer matrix. The advantages of this strategy were: no need for prior or further chemical modification of the enzyme molecules, and simplicity of design compared with the use of a conventional polymer matrix. Moreover, the fact that the film deposition was performed using a microfabrication-compatible organic plasma promised great potential for high-throughput production of bioelectronic devices.
Year
DOI
Venue
2006
10.1093/ietele/e89-c.12.1781
IEICE TRANSACTIONS ON ELECTRONICS
Keywords
Field
DocType
glucose biosensor electron transfer mediator, plasma polymerization, ferrocene, enzyme
Polymerization,Chemistry,Electron transfer,Biosensor,Plasma,Photochemistry,Redox
Journal
Volume
Issue
ISSN
E89C
12
0916-8524
Citations 
PageRank 
References 
0
0.34
0
Authors
2
Name
Order
Citations
PageRank
hitoshi114.01
Hideyuki Uehara25412.14